Brief Summary

PolyOrg, Inc., located in Leominster, MA and founded in 2003, provides comprehensive chemical synthesis services to life science companies and research universities. 

In addition to offering our 350+ catalog products, we help our customers develop new products, improve existing products, and transition their existing products from research to manufacturing.

We perform contract research, process development, custom synthesis, and manufacturing for clients in various science industries.

For inquiries or quotation requests, email

Areas of Synthesis Expertise

  • Biotinylated Labeled Compounds
  • Carbohydrates
  • Combinatorial Building Blocks
  • Fluorescent Labeling
  • Heterocycles
  • Isotopically Labeled Compounds
  • Linkers
  • Medicinal Chemistry
  • Metalloprophyrins
  • Modified DNA/RNA Monomers
  • Nucleosides
  • Nucleotides
  • Solid Support Synthesis
  • Polymer Chemistry


Chemical Reaction Expertise

  • Acylation
  • Alkylation
  • Amidation
  • Boron Chemistry
  • Catalytic Reactions
  • Carboxylation
  • Chiral Synthesis
  • Condensation
  • Cyclization
  • Friedel Craft
  • Grignard
  • Halogenation
  • Hydrogenation
  • Metal Reduction
  • Nitration
  • Oxidation
  • Reduction
  • Reductive Amination


Process Lab Equipment:

  • Glass reactors capacity up to 100 L
  • Fractional distillation equipment
  • Rotary evaporators (20 L)
  • Glass columns for small and large scale purification
  • Flammable liquid storage


Analytical Lab Capabilities:

  • HPLC
  • Flash chromatography
  • Gas chromatography
  • UV/Visible spectrometry
  • IR
  • Multi-Nuclear 400 MHz NMR
  • LCMS


ISO 9001:2015 Certification 

Catalog Products:

The catalog compounds we offer fall into the following categories: acids, acid derivatives, amidites, amines, amino acids, amino acid derivatives, anhydrides, aromatics, aziridines, biotinylated compounds, carbohydrates, chlorinated compounds, coumarins, disulfides, fine chemicals, fluorescent compounds, halogenated compounds, heterocycles, indoles, isocyanides, linkers, long chain linkers, napthyridines, nitrile, nucleobase, nucleosides (2'-OMe-Nucleosides, DMT Nucleosides), nucleoside reagents, oligonucleotide reagents, phosphates, phosphonates, phosphoramidites, PNA Backbone, PNA Intermediates/Reagents, PNA Monomers, purine, pyrenes, pyrmidines, reagents, silyl compounds, succinates, sulfonyl compounds, sulfurizing reagent, thiazoles.



PolyOrg was founded in 2003 by Saroj Roy, Ph.D. 

Prior to founding PolyOrg, Saroj was a Senior Scientist at Applied Biosystems for 6 years , a Group Leader at Hybridon for 1 year, and a Senior Scientist at Millipore/Perseptive Biosystems for 4 years.

From his 30+ years of process chemistry experience, Saroj has a track record of:
- Synthesizing novel organic and bio-organic compounds such as proteomics reagents, modified DNA/RNA intermediates, heterocyclic compounds, non-radioactive marker molecules and solid support chemistry.
-Managing teams and projects successfully and transferring processes to manufacturing.
-Reducing costs of production of these molecules through synthesis design and process development.
-Expertise in analytical instrumentation such as normal and reverse phase HPLC, multinuclear NMR, FT-IR and MS.

To connect with him on LinkedIn: